Tag: diabetes mellitus

The Ankle-Brachial Index (ABI) is a non-invasive diagnostic test used to assess vascular health by comparing blood pressure in the arms and legs. This procedure is the gold standard for detecting peripheral artery disease (PAD), a condition causing reduced blood flow to the limbs due to narrowed arteries. By utilizing a Doppler ultrasound device and standard pressure cuffs, clinicians can calculate a ratio that indicates the severity of arterial blockage, allowing for early intervention and management of cardiovascular risks.

The image displayed illustrates a severe clinical presentation of a non-healing dorsal foot ulcer in a 71-year-old male patient with a history of diabetes and smoking. This visual evidence highlights the critical nature of circulatory compromise, where a wound measuring 2.5 cm by 2.4 cm has remained chronically open for nearly two years due to insufficient blood flow. Understanding the pathophysiology behind such wounds is crucial for recognizing the advanced stages of vascular disease and the importance of multidisciplinary care in limb preservation.

Explore the vital processes of the absorptive state, where the body efficiently digests food and absorbs nutrients. This article details how insulin regulates glucose, lipids, and amino acids, and their storage in liver, muscle, and adipose cells.

Explore gluconeogenesis, a vital metabolic pathway that synthesizes glucose from non-carbohydrate precursors, ensuring a steady supply of energy for glucose-dependent organs. This intricate process is essential during fasting or prolonged exercise, playing a critical role in maintaining blood glucose homeostasis.

Unravel the complex pathways of carbohydrate metabolism, a fundamental biological process that converts glucose into usable energy for the cell. This article delves into glycolysis, the Krebs cycle, and the electron transport chain, detailing how each stage contributes to the efficient production of ATP.