Tag: circulatory system
Diagram explaining the determinants of mean arterial pressure
Mean Arterial Pressure (MAP) is a critical indicator of perfusion to vital organs, representing the average arterial pressure during a single cardiac cycle. Understanding the physiological determinants that influence MAP—ranging from cardiac output and peripheral resistance to cellular-level remodelling—is essential for grasping cardiovascular hemodynamics and clinical patient management.
Understanding the Anatomy and Function of the Arteries of the Leg
Understanding the complex network of arteries in the human leg is essential for recognizing how oxygen-rich blood reaches the lower extremities to support mobility and tissue health. This anatomical guide explores the major vascular pathways, from the groin to the foot, highlighting the critical roles each vessel plays in the peripheral circulatory system.
Venous Thrombosis Anatomy: How Blood Clots Form Around Valves
This illustrated guide analyzes the anatomical differences between a healthy vein and one compromised by a thrombus, highlighting the critical role of venous valves in circulation. By examining the mechanics of blood flow obstruction, we explore the physiological causes and dangers of venous thromboembolism as depicted in the comparative diagram.
Peripheral Arterial Disease and Digital Necrosis: Causes, Progression, and Management
Peripheral Arterial Disease (PAD) is a progressive circulatory disorder characterized by the narrowing or blockage of the arteries supplying blood to the limbs, most commonly the legs and feet. When this condition reaches an advanced stage, known as critical limb ischemia, the complete cessation of blood flow results in tissue death. The image provided illustrates a severe manifestation of this disease, where peripheral arterial disease has led to necrosis (gangrene) of multiple toes, evidenced by the blackening and mummification of the tissue due to prolonged oxygen deprivation.
Microscopic Anatomy of the Human Artery: A Histological Analysis
This bright-field photomicrograph provides a detailed cross-sectional view of a human artery, illustrating the complex, multi-layered architecture required to transport oxygenated blood under high pressure. The image distinctly reveals the vessel’s open lumen surrounded by three fundamental tissue layers—the tunica intima, tunica media, and tunica externa—each playing a critical role in vascular physiology and circulatory mechanics.
