Neuropathology

The pituitary gland, often referred to as the "master gland," is a small but vital structure located in the sella turcica of the sphenoid bone, just below the brain. This diagram illustrates the normal anatomy of the pituitary gland and the changes caused by a pituitary tumor, highlighting its potential to affect vision due to its proximity to the optic chiasm. Understanding these illustrations provides key insights into the gland's function and the clinical implications of tumor growth.

Spina bifida is a congenital condition affecting the spinal cord, resulting from the incomplete closure of the neural tube during early development. This diagram illustrates the four main types of spina bifida, providing a visual comparison of normal spinal structure and the varying degrees of malformation. Exploring these illustrations helps in recognizing the anatomical changes and their implications for those affected by this condition.

A herniated intervertebral disc occurs when the nucleus pulposus protrudes through a weakened anulus fibrosus, compressing spinal nerves and causing pain or muscle weakness, as depicted in this anatomical diagram. This article explores the structure of the intervertebral disc, the mechanisms of herniation, its symptoms, diagnosis, and treatment options, providing a comprehensive guide to understanding and managing this common spinal condition.

Osteoporosis is an age-related disorder that weakens bones, leading to a gradual collapse of the thoracic vertebrae and resulting in kyphosis, as shown in this medical image. This article explores the impact of osteoporosis on the spine, its causes, symptoms, diagnosis, and treatment options, providing a comprehensive guide for managing this condition and maintaining spinal health.

The illustration depicts a classic presentation of lumbar myelomeningocele, showing the external sac containing cerebrospinal fluid (CSF) protruding posteriorly from the lumbar region of the spine.

The image depicts a lateral (side) view of an anencephalic fetus, revealing the characteristic absence of the cranial vault and cerebral hemispheres. Anencephaly represents one of the most severe forms of neural tube defects, occurring when the rostral (head) end of the neural tube fails to close during early embryonic development. This devastating congenital malformation is incompatible with prolonged survival, with most affected newborns surviving only hours to days after birth. The lateral perspective provides medical professionals with important diagnostic visualization of the craniofacial profile typical in anencephaly, showing the absent cranial vault, exposed rudimentary brain tissue, and distinctive facial features that result from this profound developmental failure.

Anencephaly is one of the most severe neural tube defects compatible with life until birth, characterized by the absence of a major portion of the brain, skull, and scalp. The image depicts an anencephalic newborn in profile view, illustrating the distinctive craniofacial features associated with this condition. Anencephaly results from failure of the rostral (head) end of the neural tube to close during embryonic development, typically between the 23rd and 26th day of gestation. This devastating congenital anomaly is universally fatal, with most affected newborns surviving only hours to days after birth. Understanding the characteristic physical manifestations, underlying pathophysiology, and available management options is essential for healthcare professionals involved in perinatal and neonatal care.

Anencephaly is a severe congenital birth defect characterized by the absence of major portions of the brain, skull, and scalp. The image shows an anterosuperior view of an anencephalic fetus, demonstrating the distinctive facial features and cranial abnormalities that define this condition. This devastating neural tube defect occurs during early embryonic development when the neural tube fails to close properly at the cranial end, resulting in the absence of significant portions of the brain, particularly the cerebrum and cerebellum. Despite these profound structural abnormalities, the brainstem and spinal cord often remain intact, allowing for basic physiological functions in affected fetuses.

Step back in time with this rare medical photograph of a 16-year-old female patient diagnosed with hydrocephalus and occipital encephalocele from 1917. This black-and-white image provides a historical perspective on the treatment and presentation of these neurological conditions, offering valuable lessons for medical students and professionals today. Explore the clinical significance, historical context, and modern advancements related to these conditions in this detailed analysis.

The image depicts a neonate with a significant occipital encephalocele, visible as a large sac-like protrusion from the back of the infant's head. Encephalocele is a severe congenital neural tube defect characterized by herniation of brain tissue and meninges through a defect in the skull. This particular case shows a substantial occipital encephalocele with intact skin coverage and visible vascularity. The condition requires prompt multidisciplinary evaluation and neurosurgical intervention to minimize complications and optimize developmental outcomes. Early diagnosis, careful surgical planning, and comprehensive follow-up care are essential components in the management of this challenging congenital anomaly.